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TitleInsight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15.
Journal, issue, pagesBiochem. Pharmacol., Vol. 172, Page 113753-113753, Year 2019
Publish dateNov 2, 2018 (structure data deposition date)
AuthorsZhang, L. / Zhu, L. / Qu, W. / Wu, F. / Hu, M. / Xie, W. / Liu, Z. / Wang, C.
External linksBiochem. Pharmacol. / PubMed:31837310
MethodsX-ray diffraction
Resolution1.78 Å
Structure data

PDB-6ipb:
Crystal Structure of the Cofactor-binding Domain of the Human Phase II Drug Metabolism Enzyme UGT2B15
Method: X-RAY DIFFRACTION / Resolution: 1.78 Å

Chemicals

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Drug metabolism / UGT / Glycosyltransferase / Tartaric acid

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