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| Title | HBO1 is required for the maintenance of leukaemia stem cells. |
|---|---|
| Journal, issue, pages | Nature, Vol. 577, Page 266-270, Year 2020 |
| Publish date | Aug 27, 2018 (structure data deposition date) |
Authors | MacPherson, L. / Anokye, J. / Yeung, M.M. / Lam, E.Y.N. / Chan, Y.C. / Weng, C.F. / Yeh, P. / Knezevic, K. / Butler, M.S. / Hoegl, A. ...MacPherson, L. / Anokye, J. / Yeung, M.M. / Lam, E.Y.N. / Chan, Y.C. / Weng, C.F. / Yeh, P. / Knezevic, K. / Butler, M.S. / Hoegl, A. / Chan, K.L. / Burr, M.L. / Gearing, L.J. / Willson, T. / Liu, J. / Choi, J. / Yang, Y. / Bilardi, R.A. / Falk, H. / Nguyen, N. / Stupple, P.A. / Peat, T.S. / Zhang, M. / de Silva, M. / Carrasco-Pozo, C. / Avery, V.M. / Khoo, P.S. / Dolezal, O. / Dennis, M.L. / Nuttall, S. / Surjadi, R. / Newman, J. / Ren, B. / Leaver, D.J. / Sun, Y. / Baell, J.B. / Dovey, O. / Vassiliou, G.S. / Grebien, F. / Dawson, S.J. / Street, I.P. / Monahan, B.J. / Burns, C.J. / Choudhary, C. / Blewitt, M.E. / Voss, A.K. / Thomas, T. / Dawson, M.A. |
External links | Nature / PubMed:31827282 |
| Methods | X-ray diffraction |
| Resolution | 2.13 - 2.139 Å |
| Structure data | ![]() PDB-6maj: ![]() PDB-6mak: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-GOL: ![]() ChemComp-JAV: ![]() ChemComp-HOH: ![]() ChemComp-ACO: |
| Source |
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Keywords | antitumor protein/inhibitor / MYST domain / cancer inhibitor / ANTITUMOR PROTEIN / antitumor protein-inhibitor complex / antitumor protein/transferase / antitumor protein-transferase complex |
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homo sapiens (human)
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