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Structure paper

TitleAnin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Journal, issue, pagesFront Immunol, Vol. 10, Page 2572-2572, Year 2019
Publish dateMar 1, 2019 (structure data deposition date)
AuthorsMishto, M. / Mansurkhodzhaev, A. / Ying, G. / Bitra, A. / Cordfunke, R.A. / Henze, S. / Paul, D. / Sidney, J. / Urlaub, H. / Neefjes, J. ...Mishto, M. / Mansurkhodzhaev, A. / Ying, G. / Bitra, A. / Cordfunke, R.A. / Henze, S. / Paul, D. / Sidney, J. / Urlaub, H. / Neefjes, J. / Sette, A. / Zajonc, D.M. / Liepe, J.
External linksFront Immunol / PubMed:31803176
MethodsX-ray diffraction
Resolution1.4 - 1.58 Å
Structure data

PDB-6o4y:
Structure of HLA-A2:01 with peptide MM91
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

PDB-6o4z:
Structure of HLA-A2:01 with peptide MM92
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-6o51:
Structure of HLA-A2:01 with peptide MM90
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-6o53:
Structure of HLA-A2:01 with peptide MM96
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • actinomyces radingae (bacteria)
KeywordsIMMUNE SYSTEM / MHC class 1 molecule / antigen presentation / peptide interaction; PEPTIDE COMPLEX

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