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Structure paper

TitleOvercoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
Journal, issue, pagesCell Rep, Vol. 29, Page 3060-3072.e7, Year 2019
Publish dateJun 7, 2019 (structure data deposition date)
AuthorsParks, K.R. / MacCamy, A.J. / Trichka, J. / Gray, M. / Weidle, C. / Borst, A.J. / Khechaduri, A. / Takushi, B. / Agrawal, P. / Guenaga, J. ...Parks, K.R. / MacCamy, A.J. / Trichka, J. / Gray, M. / Weidle, C. / Borst, A.J. / Khechaduri, A. / Takushi, B. / Agrawal, P. / Guenaga, J. / Wyatt, R.T. / Coler, R. / Seaman, M. / LaBranche, C. / Montefiori, D.C. / Veesler, D. / Pancera, M. / McGuire, A. / Stamatatos, L.
External linksCell Rep / PubMed:31801073
MethodsX-ray diffraction
Resolution3.202 - 3.594 Å
Structure data

PDB-6p8m:
Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C
Method: X-RAY DIFFRACTION / Resolution: 3.594 Å

PDB-6p8n:
Crystal Structure of Antibody P-p1f1 in Complex with eOD-GT8
Method: X-RAY DIFFRACTION / Resolution: 3.202 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-NH4:
AMMONIUM ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus
  • mus musculus (house mouse)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / antibody / 426c / immunization

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