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Structure paper

TitleStructure and mechanism of piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 75, Page 1107-1118, Year 2019
Publish dateMay 26, 2019 (structure data deposition date)
AuthorsHasse, D. / Hulsemann, J. / Carlsson, G.H. / Valegard, K. / Andersson, I.
External linksActa Crystallogr D Struct Biol / PubMed:31793904
MethodsX-ray diffraction
Resolution1.55 - 2.25 Å
Structure data

PDB-6rtr:
Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-6rts:
Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus complexed with NAD+
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-6rtt:
Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus complexed with picolinic acid
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-6rtu:
Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus complexed with alpha-aminoadipic acid
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-6PC:
PYRIDINE-2-CARBOXYLIC ACID

ChemComp-UN1:
2-AMINOHEXANEDIOIC ACID

Source
  • streptomyces clavuligerus atcc 27064 (bacteria)
KeywordsOXIDOREDUCTASE / antibiotic biosynthesis / Streptomyces clavuligerus

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