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Structure paper

TitleGeneral structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
Journal, issue, pagesNat Commun, Vol. 10, Page 5481-5481, Year 2019
Publish dateApr 17, 2019 (structure data deposition date)
AuthorsWang, J. / Su, Y. / Iacob, R.E. / Engen, J.R. / Springer, T.A.
External linksNat Commun / PubMed:31792290
MethodsX-ray diffraction
Resolution2.66 - 2.77 Å
Structure data

PDB-6om1:
Crystal structure of an atypical integrin
Method: X-RAY DIFFRACTION / Resolution: 2.66 Å

PDB-6om2:
Crystal structure of atypical integrin alphaV beta8 with proTGF-beta1 ligand peptide
Method: X-RAY DIFFRACTION / Resolution: 2.77 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-MG:
Unknown entry

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GLY:
GLYCINE

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Integrin / TGF-beta activation

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