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Structure paper

TitleComputational design of a modular protein sense-response system.
Journal, issue, pagesScience, Vol. 366, Page 1024-1028, Year 2019
Publish dateMar 19, 2019 (structure data deposition date)
AuthorsGlasgow, A.A. / Huang, Y.M. / Mandell, D.J. / Thompson, M. / Ritterson, R. / Loshbaugh, A.L. / Pellegrino, J. / Krivacic, C. / Pache, R.A. / Barlow, K.A. ...Glasgow, A.A. / Huang, Y.M. / Mandell, D.J. / Thompson, M. / Ritterson, R. / Loshbaugh, A.L. / Pellegrino, J. / Krivacic, C. / Pache, R.A. / Barlow, K.A. / Ollikainen, N. / Jeon, D. / Kelly, M.J.S. / Fraser, J.S. / Kortemme, T.
External linksScience / PubMed:31754004
MethodsX-ray diffraction
Resolution2.208 Å
Structure data

PDB-6ob5:
Computationally-designed, modular sense/response system (S3-2D)
Method: X-RAY DIFFRACTION / Resolution: 2.208 Å

Chemicals

ChemComp-FPP:
FARNESYL DIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • unidentified (others)
KeywordsSUGAR BINDING PROTEIN / computational protein design / chemically-induced dimerization / biosensor / Rosetta

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