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Structure paper

TitleBiochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex.
Journal, issue, pagesJ. Mol. Biol., Vol. 431, Page 4910-4921, Year 2019
Publish dateMay 14, 2019 (structure data deposition date)
AuthorsAlterio, V. / Kellner, M. / Esposito, D. / Liesche-Starnecker, F. / Bua, S. / Supuran, C.T. / Monti, S.M. / Zeidler, R. / De Simone, G.
External linksJ. Mol. Biol. / PubMed:31682835
MethodsX-ray diffraction
Resolution2.79 Å
Structure data

PDB-6rps:
X-ray crystal structure of carbonic anhydrase XII complexed with a theranostic monoclonal antibody fragment
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-CD:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / Anticancer drugs / Carbonic Anhydrase XII / complex / monoclonal antibody

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