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TitleCrystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target.
Journal, issue, pagesMbio, Vol. 10, Year 2019
Publish dateSep 17, 2019 (structure data deposition date)
AuthorsLi, C. / Chai, Y. / Song, H. / Weng, C. / Qi, J. / Sun, Y. / Gao, G.F.
External linksMbio / PubMed:31662460
MethodsX-ray diffraction
Resolution1.7 - 2.301 Å
Structure data

PDB-6ky8:
Crystal structure of ASFV dUTPase
Method: X-RAY DIFFRACTION / Resolution: 2.301 Å

PDB-6ky9:
Crystal structure of ASFV dUTPase and UMP complex
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-UMP:
2'-DEOXYURIDINE 5'-MONOPHOSPHATE

Source
  • african swine fever virus
KeywordsHYDROLASE / dUTPase / ASFV / VIRAL PROTEIN / Inhibitor / Complex. dUTPase / E165R

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