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-Structure paper
Title | Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. |
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Journal, issue, pages | Sci Adv, Vol. 5, Page eaax2518-eaax2518, Year 2019 |
Publish date | Jun 12, 2019 (structure data deposition date) |
![]() | Luginina, A. / Gusach, A. / Marin, E. / Mishin, A. / Brouillette, R. / Popov, P. / Shiriaeva, A. / Besserer-Offroy, E. / Longpre, J.M. / Lyapina, E. ...Luginina, A. / Gusach, A. / Marin, E. / Mishin, A. / Brouillette, R. / Popov, P. / Shiriaeva, A. / Besserer-Offroy, E. / Longpre, J.M. / Lyapina, E. / Ishchenko, A. / Patel, N. / Polovinkin, V. / Safronova, N. / Bogorodskiy, A. / Edelweiss, E. / Hu, H. / Weierstall, U. / Liu, W. / Batyuk, A. / Gordeliy, V. / Han, G.W. / Sarret, P. / Katritch, V. / Borshchevskiy, V. / Cherezov, V. |
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Methods | X-ray diffraction |
Resolution | 2.53 - 2.7 Å |
Structure data | ![]() PDB-6rz4: ![]() PDB-6rz5: |
Chemicals | ![]() ChemComp-KNT: ![]() ChemComp-NA: ![]() ChemComp-OLC: ![]() ChemComp-OLA: ![]() ChemComp-HOH: ![]() ChemComp-ZLK: ![]() ChemComp-1PE: |
Source |
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![]() | MEMBRANE PROTEIN / GPCR / LCP / cysteinyl leukotriene / LTD4 / cyslt1 / cysltr1 / cyslt1r asthma / pranlukast / BRIL / sodium site / Cysteinyl Leukotriene Receptor 1 / cyslt1r / asthma / zafirlukast / XFEL / Serial Femtosecond Crystallography / SFX |