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Structure paper

TitleAcetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2.
Journal, issue, pagesNat Commun, Vol. 10, Page 4639-4639, Year 2019
Publish dateAug 12, 2018 (structure data deposition date)
AuthorsBhusal, R.P. / Jiao, W. / Kwai, B.X.C. / Reynisson, J. / Collins, A.J. / Sperry, J. / Bashiri, G. / Leung, I.K.H.
External linksNat Commun / PubMed:31604954
MethodsX-ray diffraction
Resolution1.8 - 2.67 Å
Structure data

PDB-6edw:
Crystal structure of Mycobacterium tuberculosis ICL2 in the apo form
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6edz:
Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA, form I
Method: X-RAY DIFFRACTION / Resolution: 2.67 Å

PDB-6ee1:
Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ACO:
ACETYL COENZYME *A

Source
  • mycobacterium tuberculosis (strain cdc 1551 / oshkosh) (bacteria)
KeywordsLYASE

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