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Structure paper

TitleStructural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans.
Journal, issue, pagesSci Rep, Vol. 9, Page 14398-14398, Year 2019
Publish dateMay 20, 2019 (structure data deposition date)
AuthorsOng, B.X. / Yoo, Y. / Han, M.G. / Park, J.B. / Choi, M.K. / Choi, Y. / Shin, J.S. / Bahn, Y.S. / Cho, H.S.
External linksSci Rep / PubMed:31591414
MethodsX-ray diffraction
Resolution2.09 - 2.4 Å
Structure data

PDB-6k3l:
Crystal structure of CX-4945 bound Cka1 from C. neoformans
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

PDB-6ko6:
Crystal structure of AMPPNP bound Cka1 from C. neoformans
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-3NG:
5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid / chemotherapy, inhibitor*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

Source
  • cryptococcus neoformans var. grubii serotype a (strain h99 / atcc 208821 / cbs 10515 / fgsc 9487) (fungus)
KeywordsTRANSFERASE / kinase

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