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Structure paper

TitleThe Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis.
Journal, issue, pagesBiochemistry, Vol. 58, Page 4343-4351, Year 2019
Publish dateAug 7, 2019 (structure data deposition date)
AuthorsFenwick, M.K. / Dong, M. / Lin, H. / Ealick, S.E.
External linksBiochemistry / PubMed:31566354
MethodsX-ray diffraction
Resolution1.768 - 3.45 Å
Structure data

PDB-6q2d:
Crystal structure of Methanobrevibacter smithii Dph2 in complex with Methanobrevibacter smithii elongation factor 2
Method: X-RAY DIFFRACTION / Resolution: 3.45 Å

PDB-6q2e:
Crystal structure of Methanobrevibacter smithii Dph2 bound to 5'-methylthioadenosine
Method: X-RAY DIFFRACTION / Resolution: 1.768 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-MTA:
5'-DEOXY-5'-METHYLTHIOADENOSINE

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • methanobrevibacter smithii (archaea)
KeywordsTRANSFERASE / Radical / S-adenosylmethionine / enzyme / iron sulfur cluster

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