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Structure paper

TitleInsights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.
Journal, issue, pagesFront Immunol, Vol. 10, Page 2097-2097, Year 2019
Publish dateJun 14, 2019 (structure data deposition date)
Authorsvan den Bos, R.M. / Pearce, N.M. / Granneman, J. / Brondijk, T.H.C. / Gros, P.
External linksFront Immunol / PubMed:31552043
MethodsX-ray diffraction
Resolution2.03 - 2.52 Å
Structure data

PDB-6s08:
Crystal Structure of Properdin (TSR domains N1 & 456)
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

PDB-6s0a:
Crystal Structure of Properdin (TSR domains N12 & 456)
Method: X-RAY DIFFRACTION / Resolution: 2.52 Å

PDB-6s0b:
Crystal Structure of Properdin in complex with the CTC domain of C3/C3b
Method: X-RAY DIFFRACTION / Resolution: 2.312 Å

Chemicals

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-NA:
Unknown entry

ChemComp-FUC:
alpha-L-fucopyranose

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / INNATE IMMUNITY / COMPLEMENT

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