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-Structure paper
Title | NeuNAc Oxime: A Slow-Binding and Effectively Irreversible Inhibitor of the Sialic Acid Synthase NeuB. |
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Journal, issue, pages | Biochemistry, Vol. 58, Page 4236-4245, Year 2019 |
Publish date | Jul 8, 2019 (structure data deposition date) |
Authors | Popovic, V. / Morrison, E. / Rosanally, A.Z. / Balachandran, N. / Senson, A.W. / Szabla, R. / Junop, M.S. / Berti, P.J. |
External links | Biochemistry / PubMed:31549502 |
Methods | X-ray diffraction |
Resolution | 1.85 - 2.4 Å |
Structure data | PDB-6ppw: PDB-6ppx: PDB-6ppy: PDB-6ppz: |
Chemicals | ChemComp-MG: ChemComp-MLT: ChemComp-HOH: ChemComp-OVY: ChemComp-MN9: ChemComp-MN: ChemComp-PO4: |
Source |
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Keywords | BIOSYNTHETIC PROTEIN / TRANSFERASE / NeuB / sialic acid synthase / N-acetylneuraminate synthase / inhibitor complex / N-acetyl-neuraminate synthase / NeuNAc oxime / Siac / phosphate / N-acetylmannosamine |