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Structure paper

TitleMolecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
Journal, issue, pagesGenes Dev., Vol. 33, Page 1355-1360, Year 2019
Publish dateJul 10, 2019 (structure data deposition date)
AuthorsPeter, D. / Ruscica, V. / Bawankar, P. / Weber, R. / Helms, S. / Valkov, E. / Igreja, C. / Izaurralde, E.
External linksGenes Dev. / PubMed:31439631
MethodsX-ray diffraction
Resolution2.21 - 2.41 Å
Structure data

PDB-6s8r:
D. melanogaster RNA helicase Me31B in complex with GIGYF
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

PDB-6s8s:
Extended structure of the human DDX6 C-terminal domain in complex with an EDC3 FDF peptide
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CXS:
3-CYCLOHEXYL-1-PROPYLSULFONIC ACID / pH buffer*YM

Source
  • drosophila melanogaster (fruit fly)
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / Translation / Translational control / mRNA decay / miRNA

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