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TitleMakes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 116, Page 18031-18040, Year 2019
Publish dateOct 3, 2018 (structure data deposition date)
AuthorsLee, Y. / Kim, B.S. / Choi, S. / Lee, E.Y. / Park, S. / Hwang, J. / Kwon, Y. / Hyun, J. / Lee, C. / Kim, J.F. ...Lee, Y. / Kim, B.S. / Choi, S. / Lee, E.Y. / Park, S. / Hwang, J. / Kwon, Y. / Hyun, J. / Lee, C. / Kim, J.F. / Eom, S.H. / Kim, M.H.
External linksProc. Natl. Acad. Sci. USA / PubMed:31427506
MethodsX-ray diffraction
Resolution2.1 - 3.5 Å
Structure data

PDB-6ii0:
Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

PDB-6ii2:
Crystal structure of alpha-beta hydrolase (ABH) and Makes Caterpillars Floppy (MCF)-Like effectors of Vibrio vulnificus MO6-24/O
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-6ii6:
Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O in complex with a human ADP-ribosylation factor 3 (ARF3)
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6imp:
Crystal structure of alpha-beta hydrolase (ABH) from Vibrio vulnificus
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

Source
  • vibrio vulnificus (bacteria)
  • homo sapiens (human)
  • vibrio vulnificus mo6-24/o (bacteria)
KeywordsTOXIN / MCF / MARTX TOXIN / EFFECTOR DOMAIN / ABH-MCF / TOXIN/PROTEIN BINDING / ARF3 / TOXIN-HOST PROTEIN COMPLEX / TOXIN-PROTEIN BINDING complex / Virulence / hydrolase / alpha-beta fold / toxins

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