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TitleA strategy for the selection of monovalent antibodies that span protein dimer interfaces.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 13876-13886, Year 2019
Publish dateMar 27, 2019 (structure data deposition date)
AuthorsSpangler, J.B. / Moraga, I. / Jude, K.M. / Savvides, C.S. / Garcia, K.C.
External linksJ. Biol. Chem. / PubMed:31387945
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-6oel:
Engineered Fab bound to IL-4 receptor
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-NO3:
NITRATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / cytokine receptor / fab

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