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Structure paper

TitleAlternative conformations of a major antigenic site on RSV F.
Journal, issue, pagesPlos Pathog., Vol. 15, Page e1007944-e1007944, Year 2019
Publish dateMay 4, 2018 (structure data deposition date)
AuthorsJones, H.G. / Battles, M.B. / Lin, C.C. / Bianchi, S. / Corti, D. / McLellan, J.S.
External linksPlos Pathog. / PubMed:31306469
MethodsX-ray diffraction
Resolution1.7 - 3.501 Å
Structure data

PDB-6dc3:
RSV prefusion F bound to RSD5 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.501 Å

PDB-6dc4:
RSV-neutralizing human antibody AM22
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6dc5:
RSV prefusion F in complex with AM22 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-CD:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
  • human respiratory syncytial virus a (strain a2)
  • human immunodeficiency virus 1
  • unidentified (others)
KeywordsIMMUNE SYSTEM / Antibody / Viral glycoprotein / Complex / Fab / Viral fusion glycoprotein / human antibody

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