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Structure paper

TitleStructural Basis of Protein Kinase R Autophosphorylation.
Journal, issue, pagesBiochemistry, Vol. 58, Page 2967-2977, Year 2019
Publish dateApr 16, 2018 (structure data deposition date)
AuthorsMayo, C.B. / Erlandsen, H. / Mouser, D.J. / Feinstein, A.G. / Robinson, V.L. / May, E.R. / Cole, J.L.
External linksBiochemistry / PubMed:31246429
MethodsX-ray diffraction
Resolution2.6 - 3.1 Å
Structure data

PDB-6d3k:
Crystal structure of unphosphorylated human PKR kinase domain in complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6d3l:
Crystal structure of unphosphorylated human PKR
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / unphosphorylated / kinase / complex / activation loop swapping / dimer / apo

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