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Structure paper

TitleA temporal thymic selection switch and ligand binding kinetics constrain neonatal Foxp3+Tregcell development.
Journal, issue, pagesNat. Immunol., Vol. 20, Page 1046-1058, Year 2019
Publish dateSep 25, 2018 (structure data deposition date)
AuthorsStadinski, B.D. / Blevins, S.J. / Spidale, N.A. / Duke, B.R. / Huseby, P.G. / Stern, L.J. / Huseby, E.S.
External linksNat. Immunol. / PubMed:31209405
MethodsX-ray diffraction
Resolution2.662 - 3.355 Å
Structure data

PDB-6mkd:
4699 TCR bound to I-Ab Padi4
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-6mkr:
5287 TCR bound to IAb Padi4
Method: X-RAY DIFFRACTION / Resolution: 3.355 Å

PDB-6mng:
4738 TCR bound to IAb Padi4
Method: X-RAY DIFFRACTION / Resolution: 2.662 Å

PDB-6mnm:
6256 TCR bound to I-Ab Padi4
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-6mnn:
6236 TCR bound to I-Ab Padi4
Method: X-RAY DIFFRACTION / Resolution: 2.83 Å

PDB-6mno:
6235 TCR bound to I-Ab Padi4
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / T cell receptor / Major Histocompatibility Complex

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