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Title | Crystal structures of the recombinant beta-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics. |
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Journal, issue, pages | Acta Crystallogr D Struct Biol, Vol. 75, Page 578-591, Year 2019 |
Publish date | Jun 15, 2018 (structure data deposition date) |
![]() | Pathak, M. / Manna, R. / Li, C. / Kaira, B.G. / Hamad, B.K. / Belviso, B.D. / Bonturi, C.R. / Dreveny, I. / Fischer, P.M. / Dekker, L.V. ...Pathak, M. / Manna, R. / Li, C. / Kaira, B.G. / Hamad, B.K. / Belviso, B.D. / Bonturi, C.R. / Dreveny, I. / Fischer, P.M. / Dekker, L.V. / Oliva, M.L.V. / Emsley, J. |
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Methods | X-ray diffraction |
Resolution | 2.54 - 4 Å |
Structure data | ![]() PDB-6gt6: ![]() PDB-6qf7: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-CYS: ![]() ChemComp-HOH: ![]() ChemComp-NAG: ![]() ChemComp-0G6: |
Source |
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![]() | BLOOD CLOTTING / human coagulation factor XIIa / hydrolase / serine protease / coagulation factor XII; serine protease; crystal structure; inhibitor complex |