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TitleBiocompatible Macrocyclization between Cysteine and 2-Cyanopyridine Generates Stable Peptide Inhibitors.
Journal, issue, pagesOrg. Lett., Vol. 21, Page 4709-4712, Year 2019
Publish dateMar 28, 2019 (structure data deposition date)
AuthorsNitsche, C. / Onagi, H. / Quek, J.P. / Otting, G. / Luo, D. / Huber, T.
External linksOrg. Lett. / PubMed:31188009
MethodsX-ray diffraction
Resolution1.951 Å
Structure data

PDB-6jpw:
Crystal structure of Zika NS2B-NS3 protease with compound 1C
Method: X-RAY DIFFRACTION / Resolution: 1.951 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • zika virus
  • zika virus (strain mr 766)
  • synthetic construct (others)
KeywordsVIRAL PROTEIN / Viral protease / Protease inhibitor complex

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