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Structure paper

TitleAn enzymatic pathway in the human gut microbiome that converts A to universal O type blood.
Journal, issue, pagesNat Microbiol, Vol. 4, Page 1475-1485, Year 2019
Publish dateNov 8, 2018 (structure data deposition date)
AuthorsRahfeld, P. / Sim, L. / Moon, H. / Constantinescu, I. / Morgan-Lang, C. / Hallam, S.J. / Kizhakkedathu, J.N. / Withers, S.G.
External linksNat Microbiol / PubMed:31182795
MethodsX-ray diffraction
Resolution1.3 - 1.6 Å
Structure data

PDB-6n1a:
Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-6n1b:
Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii in complex with blood group B trisaccharide
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • flavonifractor plautii (bacteria)
KeywordsHYDROLASE / N-acetylgalactosamine deacetylase / A Blood antigen / CAZy

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