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TitleThe Highly Recurrent PP2A A alpha-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis.
Journal, issue, pagesCancer Res., Vol. 79, Page 4242-4257, Year 2019
Publish dateAug 16, 2018 (structure data deposition date)
AuthorsTaylor, S.E. / O'Connor, C.M. / Wang, Z. / Shen, G. / Song, H. / Leonard, D. / Sangodkar, J. / LaVasseur, C. / Avril, S. / Waggoner, S. ...Taylor, S.E. / O'Connor, C.M. / Wang, Z. / Shen, G. / Song, H. / Leonard, D. / Sangodkar, J. / LaVasseur, C. / Avril, S. / Waggoner, S. / Zanotti, K. / Armstrong, A.J. / Nagel, C. / Resnick, K. / Singh, S. / Jackson, M.W. / Xu, W. / Haider, S. / DiFeo, A. / Narla, G.
External linksCancer Res. / PubMed:31142515
MethodsX-ray diffraction
Resolution3.4 Å
Structure data

PDB-6ef4:
Crystal structure of mouse PP2A Aalpha P179R mutant
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Source
  • mus musculus (house mouse)
KeywordsPROTEIN BINDING / PP2A / Aalpha

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