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Structure paper

TitleThe extracellular gate shapes the energy profile of an ABC exporter.
Journal, issue, pagesNat Commun, Vol. 10, Page 2260-2260, Year 2019
Publish dateMar 1, 2019 (structure data deposition date)
AuthorsHutter, C.A.J. / Timachi, M.H. / Hurlimann, L.M. / Zimmermann, I. / Egloff, P. / Goddeke, H. / Kucher, S. / Stefanic, S. / Karttunen, M. / Schafer, L.V. ...Hutter, C.A.J. / Timachi, M.H. / Hurlimann, L.M. / Zimmermann, I. / Egloff, P. / Goddeke, H. / Kucher, S. / Stefanic, S. / Karttunen, M. / Schafer, L.V. / Bordignon, E. / Seeger, M.A.
External linksNat Commun / PubMed:31113958
MethodsX-ray diffraction
Resolution3.12 - 4.23 Å
Structure data

PDB-6quz:
Structure of ATPgS-bound outward-facing TM287/288 in complex with sybody Sb_TM35
Method: X-RAY DIFFRACTION / Resolution: 3.21 Å

PDB-6qv0:
Structure of ATP-bound outward-facing TM287/288 in complex with sybody Sb_TM35
Method: X-RAY DIFFRACTION / Resolution: 3.12 Å

PDB-6qv1:
Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM1
Method: X-RAY DIFFRACTION / Resolution: 3.48 Å

PDB-6qv2:
Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM#2
Method: X-RAY DIFFRACTION / Resolution: 4.23 Å

Chemicals

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

Source
  • thermotoga maritima (strain atcc 43589 / msb8 / dsm 3109 / jcm 10099) (bacteria)
  • synthetic construct (others)
  • vicugna pacos (alpaca)
KeywordsMEMBRANE PROTEIN / ABC exporter / ABC transporter / Membrane Transporter / sybody / nanobody

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