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Structure paper

TitleAntibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Journal, issue, pagesCell, Vol. 177, Page 1124-1135.e16, Year 2019
Publish dateJul 18, 2018 (structure data deposition date)
AuthorsWatanabe, A. / McCarthy, K.R. / Kuraoka, M. / Schmidt, A.G. / Adachi, Y. / Onodera, T. / Tonouchi, K. / Caradonna, T.M. / Bajic, G. / Song, S. ...Watanabe, A. / McCarthy, K.R. / Kuraoka, M. / Schmidt, A.G. / Adachi, Y. / Onodera, T. / Tonouchi, K. / Caradonna, T.M. / Bajic, G. / Song, S. / McGee, C.E. / Sempowski, G.D. / Feng, F. / Urick, P. / Kepler, T.B. / Takahashi, Y. / Harrison, S.C. / Kelsoe, G.
External linksCell / PubMed:31100267
MethodsX-ray diffraction
Resolution2 - 2.25 Å
Structure data

PDB-6e4x:
Human antibody S5V2-29 in complex with influenza hemagglutinin A/Texas/50/2012 (H3N2)
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-6e56:
Human antibody H2214 in complex with influenza hemagglutinin A/Aichi/2/1968 (X-31) (H3N2)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

Source
  • influenza a virus (a/texas/50/2012(h3n2))
  • homo sapiens (human)
  • influenza a virus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / influenza antibody / VIRAL PROTEIN-IMMUNE SYSTEM complex

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