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TitleCrystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Journal, issue, pagesImmunity, Vol. 51, Page 43-, Year 2019
Publish dateDec 3, 2018 (structure data deposition date)
AuthorsLiu, Z. / Wang, C. / Yang, J. / Zhou, B. / Yang, R. / Ramachandran, R. / Abbott, D.W. / Xiao, T.S.
External linksImmunity / PubMed:31097341
MethodsX-ray diffraction
Resolution3.3 - 3.5 Å
Structure data

PDB-6n9n:
Crystal structure of murine GSDMD
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-6n9o:
Crystal structure of human GSDMD
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Pyroptosis / gasdermin D / inflammasome / autoinhibition

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