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Structure paper

TitleStructural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 116, Page 10804-10812, Year 2019
Publish dateNov 30, 2018 (structure data deposition date)
AuthorsAlmagor, L. / Ufimtsev, I.S. / Ayer, A. / Li, J. / Weis, W.I.
External linksProc. Natl. Acad. Sci. USA / PubMed:31088962
MethodsX-ray diffraction
Resolution1.91 - 3.9 Å
Structure data

PDB-6n8p:
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). Unphosphorylated, crystal form 1.
Method: X-RAY DIFFRACTION / Resolution: 3.193 Å

PDB-6n8q:
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). Unphosphorylated, crystal form 2.
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6n8r:
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC phosphorylated, crystal form 2.
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

PDB-6n8s:
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC phosphorylated, crystal form 3.
Method: X-RAY DIFFRACTION / Resolution: 3.9 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / Lgl / Polarity / beta propeller

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