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TitleStructural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.
Journal, issue, pagesVirology, Vol. 533, Page 21-33, Year 2019
Publish dateJun 14, 2016 (structure data deposition date)
AuthorsKanitz, M. / Blanck, S. / Heine, A. / Gulyaeva, A.A. / Gorbalenya, A.E. / Ziebuhr, J. / Diederich, W.E.
External linksVirology / PubMed:31078932
MethodsX-ray diffraction
Resolution1.94 - 2.299 Å
Structure data

PDB-5lac:
SeMet Labeled Derivative of Cavally Virus 3CL Protease
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-5lak:
Ligand-bound structure of Cavally Virus 3CL Protease
Method: X-RAY DIFFRACTION / Resolution: 2.299 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • cavally virus
  • synthetic construct (others)
KeywordsHYDROLASE / SeMet derivative / Protease / Mesonivirus / 3CL / peptide-bound

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