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Structure paper

TitleNanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors.
Journal, issue, pagesNeuron, Vol. 102, Page 976-, Year 2019
Publish dateMay 15, 2018 (structure data deposition date)
AuthorsDawe, G.B. / Kadir, M.F. / Venskutonyte, R. / Perozzo, A.M. / Yan, Y. / Alexander, R.P.D. / Navarrete, C. / Santander, E.A. / Arsenault, M. / Fuentes, C. ...Dawe, G.B. / Kadir, M.F. / Venskutonyte, R. / Perozzo, A.M. / Yan, Y. / Alexander, R.P.D. / Navarrete, C. / Santander, E.A. / Arsenault, M. / Fuentes, C. / Aurousseau, M.R.P. / Frydenvang, K. / Barrera, N.P. / Kastrup, J.S. / Edwardson, J.M. / Bowie, D.
External linksNeuron / PubMed:31053408
MethodsX-ray diffraction
Resolution1.75 - 1.948 Å
Structure data

PDB-6giv:
Structure of GluA2-N775S ligand-binding domain (S1S2J) in complex with glutamate and Rubidium Bromide at 1.75 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-6gl4:
Structure of GluA2o ligand-binding domain (S1S2J) in complex with glutamate and sodium bromide at 1.95 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.948 Å

Chemicals

ChemComp-GLU:
GLUTAMIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-BR:
BROMIDE ION

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

Source
  • rattus norvegicus (Norway rat)
KeywordsMEMBRANE PROTEIN / Ionotropic glutamate receptor / GluA2-N775S ligand-binding domain / agonist / bromide ions / GluA2o ligand-binding domain

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