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Structure paper

TitleInsight into microtubule nucleation from tubulin-capping proteins.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 116, Page 9859-9864, Year 2019
Publish dateJun 21, 2018 (structure data deposition date)
AuthorsCampanacci, V. / Urvoas, A. / Cantos-Fernandes, S. / Aumont-Nicaise, M. / Arteni, A.A. / Velours, C. / Valerio-Lepiniec, M. / Dreier, B. / Pluckthun, A. / Pilon, A. ...Campanacci, V. / Urvoas, A. / Cantos-Fernandes, S. / Aumont-Nicaise, M. / Arteni, A.A. / Velours, C. / Valerio-Lepiniec, M. / Dreier, B. / Pluckthun, A. / Pilon, A. / Pous, C. / Minard, P. / Gigant, B.
External linksProc. Natl. Acad. Sci. USA / PubMed:31036638
MethodsX-ray diffraction
Resolution2.69 - 3.5 Å
Structure data

PDB-6gvm:
Tubulin:F3II DARPin complex
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-6gvn:
Tubulin:TM-3 DARPin complex
Method: X-RAY DIFFRACTION / Resolution: 2.69 Å

PDB-6gx7:
Tubulin-CopN-alphaRep complex
Method: X-RAY DIFFRACTION / Resolution: 3.19 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-SO4:
SULFATE ION

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • ovis aries (sheep)
  • synthetic construct (others)
  • chlamydia pneumoniae (bacteria)
KeywordsCELL CYCLE / microtubule / DARPIN / STATHmin-like protein / ALPHAREP / COPN

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