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Structure paper

TitleStructural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
Journal, issue, pagesJ. Cell Biol., Vol. 218, Page 1839-1852, Year 2019
Publish dateDec 14, 2018 (structure data deposition date)
AuthorsAksu, M. / Trakhanov, S. / Vera Rodriguez, A. / Gorlich, D.
External linksJ. Cell Biol. / PubMed:31023722
MethodsX-ray diffraction
Resolution2.994 - 4.53 Å
Structure data

PDB-6q82:
Crystal structure of the biportin Pdr6 in complex with RanGTP
Method: X-RAY DIFFRACTION / Resolution: 2.994 Å

PDB-6q83:
Crystal structure of the biportin Pdr6 in complex with UBC9
Method: X-RAY DIFFRACTION / Resolution: 4.53 Å

PDB-6q84:
Crystal structure of RanGTP-Pdr6-eIF5A export complex
Method: X-RAY DIFFRACTION / Resolution: 3.7 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / Importin-Beta family / biportin / nuclear transport / GTPase / nuclear import / SUMOylation / nuclear export / translation factor

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