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TitleStructural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Journal, issue, pagesFebs Open Bio, Vol. 9, Page 1042-1051, Year 2019
Publish dateNov 6, 2017 (structure data deposition date)
AuthorsFoss, D.V. / Schirle, N.T. / MacRae, I.J. / Pezacki, J.P.
External linksFebs Open Bio / PubMed:31021526
MethodsX-ray diffraction
Resolution2.198 - 2.58 Å
Structure data

PDB-6bjg:
CIRV p19 mutant T111H in complex with siRNA
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

PDB-6bjh:
CIRV p19 mutant T111S in complex with siRNA
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

PDB-6bjv:
CIRV p19 protein in complex with siRNA
Method: X-RAY DIFFRACTION / Resolution: 2.198 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • carnation italian ringspot virus
  • lampyridae (fireflies)
KeywordsRNA BINDING PROTEIN / Viral Suppressor / RNA silencing siRNA binding protein p19 / altered affinity for microRNA / RNA silencing siRNA / high affinity for human miRNA-122

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