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-Structure paper
Title | Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R. |
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Journal, issue, pages | Biomolecules, Vol. 9, Year 2019 |
Publish date | Mar 16, 2019 (structure data deposition date) |
Authors | Pozzi, C. / Lopresti, L. / Santucci, M. / Costi, M.P. / Mangani, S. |
External links | Biomolecules / PubMed:30987202 |
Methods | X-ray diffraction |
Resolution | 2.55 Å |
Structure data | PDB-6r2e: |
Chemicals | ChemComp-SO4: ChemComp-FFO: ChemComp-CL: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / human thymidylate synthase / folate pathway / Q62R / interface variant |