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TitleBAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association.
Journal, issue, pagesCell Rep, Vol. 27, Page 359-373.e6, Year 2019
Publish dateAug 5, 2018 (structure data deposition date)
AuthorsDengler, M.A. / Robin, A.Y. / Gibson, L. / Li, M.X. / Sandow, J.J. / Iyer, S. / Webb, A.I. / Westphal, D. / Dewson, G. / Adams, J.M.
External linksCell Rep / PubMed:30970242
MethodsX-ray diffraction
Resolution2.023 Å
Structure data

PDB-6eb6:
Crystal structure of BAX W139A monomer
Method: X-RAY DIFFRACTION / Resolution: 2.023 Å

Chemicals

ChemComp-FMT:
FORMIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / BAX / inactive monomer

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