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Structure paper

TitleClassification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Journal, issue, pagesNat Commun, Vol. 10, Page 1528-1528, Year 2019
Publish dateAug 1, 2017 (structure data deposition date)
AuthorsChandra, M. / Chin, Y.K. / Mas, C. / Feathers, J.R. / Paul, B. / Datta, S. / Chen, K.E. / Jia, X. / Yang, Z. / Norwood, S.J. ...Chandra, M. / Chin, Y.K. / Mas, C. / Feathers, J.R. / Paul, B. / Datta, S. / Chen, K.E. / Jia, X. / Yang, Z. / Norwood, S.J. / Mohanty, B. / Bugarcic, A. / Teasdale, R.D. / Henne, W.M. / Mobli, M. / Collins, B.M.
External linksNat Commun / PubMed:30948714
MethodsNMR (solution) / X-ray diffraction
Resolution2.009 - 2.834 Å
Structure data

PDB-5woe:
Solution structure of the sorting nexin 25 phox-homology domain
Method: SOLUTION NMR

PDB-6ecm:
Crystal Structure of SNX15 PX domain in domain swapped conformation
Method: X-RAY DIFFRACTION / Resolution: 2.353 Å

PDB-6edx:
Crystal Structure of SGK3 PX domain
Method: X-RAY DIFFRACTION / Resolution: 2.009 Å

PDB-6ee0:
Crystal Structure of SNX23 PX domain
Method: X-RAY DIFFRACTION / Resolution: 2.518 Å

PDB-6mbi:
Crystal Structure of SNX15 PX domain in domain swapped conformation form 2
Method: X-RAY DIFFRACTION / Resolution: 2.834 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / endosome / Mdm1 / PX domain / PXA domain / PXC domain / RGS domain / sorting nexin / SNX / SNX13 / SNX14 / SNX19 / SNX25 / LIPID BINDING PROTEIN / trafficking / TRANSFERASE

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