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Structure paper

TitleMitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Journal, issue, pagesNat Commun, Vol. 10, Page 1473-1473, Year 2019
Publish dateNov 17, 2017 (structure data deposition date)
AuthorsChoi, E. / Kikuchi, S. / Gao, H. / Brodzik, K. / Nassour, I. / Yopp, A. / Singal, A.G. / Zhu, H. / Yu, H.
External linksNat Commun / PubMed:30931927
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-6bnt:
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsENDOCYTOSIS / AP2 mu1 / IRS1

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