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TitleA cytosine modification mechanism revealed by the structure of a ternary complex of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate.
Journal, issue, pagesIucrj, Vol. 6, Page 206-217, Year 2019
Publish dateJul 12, 2018 (structure data deposition date)
AuthorsPark, S.H. / Suh, S.W. / Song, H.K.
External linksIucrj / PubMed:30867918
MethodsX-ray diffraction
Resolution1.9 - 2.01 Å
Structure data

PDB-6a9a:
Ternary complex crystal structure of dCH with dCMP and THF
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6a9b:
T4 dCMP hydroxymethylase structure solved by I-SAD using a home source
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

Chemicals

ChemComp-IOD:
IODIDE ION

ChemComp-DCM:
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE

ChemComp-THG:
(6S)-5,6,7,8-TETRAHYDROFOLATE

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

Source
  • enterobacteria phage t4 (virus)
KeywordsTRANSFERASE / pyrimidine hydroxymethylase

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