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Structure paper

TitleEfficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation.
Journal, issue, pagesSci Rep, Vol. 9, Page 3177-3177, Year 2019
Publish dateDec 11, 2017 (structure data deposition date)
AuthorsCastellvi, A. / Crespo, I. / Crosas, E. / Camara-Artigas, A. / Gavira, J.A. / Aranda, M.A.G. / Pares, X. / Farres, J. / Juanhuix, J.
External linksSci Rep / PubMed:30816220
MethodsX-ray diffraction
Resolution0.92 - 1.17 Å
Structure data

PDB-6f7r:
AKR1B1 at 0.03 MGy radiation dose.
Method: X-RAY DIFFRACTION / Resolution: 0.92 Å

PDB-6f81:
AKR1B1 at 0.75 MGy radiation dose.
Method: X-RAY DIFFRACTION / Resolution: 0.97 Å

PDB-6f82:
AKR1B1 at 1.65 MGy radiation dose.
Method: X-RAY DIFFRACTION / Resolution: 1.03 Å

PDB-6f84:
AKR1B1 at 2.55 MGy radiation dose.
Method: X-RAY DIFFRACTION / Resolution: 1.09 Å

PDB-6f8o:
AKR1B1 at 3.45 MGy radiation dose.
Method: X-RAY DIFFRACTION / Resolution: 1.17 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / oxidative stress / radiation damage / diabetes / non-genetic mutation

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