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Structure paper

TitleStructural basis for KCTD-mediated rapid desensitization of GABABsignalling.
Journal, issue, pagesNature, Vol. 567, Page 127-131, Year 2019
Publish dateAug 22, 2018 (structure data deposition date)
AuthorsZheng, S. / Abreu, N. / Levitz, J. / Kruse, A.C.
External linksNature / PubMed:30814734
MethodsX-ray diffraction
Resolution3.2 - 3.71 Å
Structure data

PDB-6m8r:
Crystal structure of the KCTD16 BTB domain in complex with GABAB2 peptide
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-6m8s:
Crystal structure of the KCTD12 H1 domain in complex with Gbeta1gamma2 subunits
Method: X-RAY DIFFRACTION / Resolution: 3.71 Å

Chemicals

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / pentamer / BTB domain / SIGNALING PROTEIN / beta-propeller / homopentamer / GABAB desensitization

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