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TitleStructure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
Journal, issue, pagesSci Signal, Vol. 12, Year 2019
Publish dateApr 27, 2018 (structure data deposition date)
AuthorsBandekar, S.J. / Arang, N. / Tully, E.S. / Tang, B.A. / Barton, B.L. / Li, S. / Gutkind, J.S. / Tesmer, J.J.G.
External linksSci Signal / PubMed:30783010
MethodsX-ray diffraction
Resolution2.65 Å
Structure data

PDB-6d8z:
Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / RhoGEF / Dbl Family member / Dbl Homology / Pleckstrin Homology

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