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Structure paper

TitleMolecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus.
Journal, issue, pagesJ. Virol., Vol. 93, Year 2019
Publish dateJan 10, 2019 (structure data deposition date)
AuthorsYang, X. / Qi, J. / Peng, R. / Dai, L. / Gould, E.A. / Gao, G.F. / Tien, P.
External linksJ. Virol. / PubMed:30760569
MethodsX-ray diffraction
Resolution1.8 - 3.6 Å
Structure data

PDB-6j5c:
Louping ill virus envelope protein
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

PDB-6j5d:
Complex structure of MAb 4.2-scFv with louping ill virus envelope protein Domain III
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6j5f:
Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein Domain III
Method: X-RAY DIFFRACTION / Resolution: 1.801 Å

PDB-6j5g:
Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein
Method: X-RAY DIFFRACTION / Resolution: 3.291 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • louping ill virus
  • mus musculus (house mouse)
  • tick-borne encephalitis virus
  • tick-borne encephalitis virus european subtype (strain neudoerfl)
KeywordsVIRAL PROTEIN / tick-borne flavivirus / envelope protein / VIRAL PROTEIN/IMMUNE SYSTEM / protective and neutralizing antibody / flavivirus envelope protein / ANTIVIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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