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Structure paper

TitleMechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Journal, issue, pagesNat. Chem. Biol., Vol. 15, Page 285-294, Year 2019
Publish dateJun 18, 2018 (structure data deposition date)
AuthorsJurenas, D. / Van Melderen, L. / Garcia-Pino, A.
External linksNat. Chem. Biol. / PubMed:30718814
MethodsX-ray diffraction
Resolution2.49 - 3.357 Å
Structure data

PDB-6gto:
Structure of the AtaR antitoxin
Method: X-RAY DIFFRACTION / Resolution: 2.97 Å

PDB-6gtp:
Structure of the AtaT Y144F mutant toxin
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6gtq:
Structure of the AtaT Y144F mutant toxin bound to the C-terminus of the antitoxin AtaR
Method: X-RAY DIFFRACTION / Resolution: 2.49 Å

PDB-6gtr:
Structure of the AtaT Y144F mutant toxin bound to the C-terminus of the antitoxin AtaR and Acetyl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

PDB-6gts:
Structure of the AtaT-AtaR complex bound DNA
Method: X-RAY DIFFRACTION / Resolution: 3.357 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-ACO:
ACETYL COENZYME *A

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-FLC:
CITRATE ANION

ChemComp-IOD:
IODIDE ION

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION / antitoxin / transcription factor / ribbon-helix-helix / RHH / bacterial repressor / TA toxin / N-acetyl transferase / toxin-antitoxin complex / protein-nucleic acid complex

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