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Structure paper

TitleStructure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae.
Journal, issue, pagesMbio, Vol. 10, Year 2019
Publish dateAug 20, 2018 (structure data deposition date)
AuthorsRued, B.E. / Alcorlo, M. / Edmonds, K.A. / Martinez-Caballero, S. / Straume, D. / Fu, Y. / Bruce, K.E. / Wu, H. / Havarstein, L.S. / Hermoso, J.A. ...Rued, B.E. / Alcorlo, M. / Edmonds, K.A. / Martinez-Caballero, S. / Straume, D. / Fu, Y. / Bruce, K.E. / Wu, H. / Havarstein, L.S. / Hermoso, J.A. / Winkler, M.E. / Giedroc, D.P.
External linksMbio / PubMed:30696736
MethodsX-ray diffraction / NMR (solution)
Resolution2 - 2.3 Å
Structure data

PDB-6he6:
Crystal structure of Extracellular Domain 1 (ECD1) of FtsX from S. pneumonie in complex with dodecane-trimethylamine
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6hee:
Crystal structure of Extracellular Domain 1 (ECD1) of FtsX from S. pneumonie in complex with undecyl-maltoside
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6hfx:
Crystal structure of Extracellular Domain 1 (ECD1) of FtsX from S. pneumonie in complex with n-decyl-B-D-maltoside
Method: X-RAY DIFFRACTION / Resolution: 2.16 Å

PDB-6mk7:
Solution structure of the large extracellular loop of FtsX in Streptococcus pneumoniae
Method: SOLUTION NMR

Chemicals

ChemComp-CAT:
DODECANE-TRIMETHYLAMINE

ChemComp-HOH:
WATER

ChemComp-UMQ:
UNDECYL-MALTOSIDE / detergent*YM

ChemComp-SO4:
SULFATE ION

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-DMU:
DECYL-BETA-D-MALTOPYRANOSIDE / detergent*YM

Source
  • streptococcus pneumoniae (bacteria)
  • streptococcus pneumoniae serotype 2 (strain d39 / nctc 7466) (bacteria)
KeywordsCELL CYCLE / cell division / MEMBRANE PROTEIN / Divisome / CELL WALL / PEPTIDOGLYCAN

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