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Structure paper

TitleTalaromyces marneffeiMp1 protein, a novel virulence factor, carries two arachidonic acid-binding domains to suppress inflammatory responses in hosts.
Journal, issue, pagesInfect. Immun., Year 2019
Publish dateOct 13, 2015 (structure data deposition date)
AuthorsLam, W.H. / Sze, K.H. / Ke, Y. / Tse, M.K. / Zhang, H. / Woo, P.C.Y. / Lau, S.K.P. / Lau, C.C.Y. / Xu, S. / Lai, P.M. ...Lam, W.H. / Sze, K.H. / Ke, Y. / Tse, M.K. / Zhang, H. / Woo, P.C.Y. / Lau, S.K.P. / Lau, C.C.Y. / Xu, S. / Lai, P.M. / Zhou, T. / Antonyuk, S.V. / Kao, R.Y.T. / Yuen, K.Y. / Hao, Q.
External linksInfect. Immun. / PubMed:30670555
MethodsX-ray diffraction
Resolution1.8 - 4.2 Å
Structure data

PDB-5e7x:
Ligand binding domain 1 of Penicillium marneffei MP1 protein in complex with palmitic acid
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-5ecf:
Ligand binding domain 1 of Penicillium marneffei MP1 protein complexed with arachidonic acids
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6j6f:
Ligand binding domain 1 and 2 of Talaromyces marneffei Mp1 protein
Method: X-RAY DIFFRACTION / Resolution: 4.2 Å

Chemicals

ChemComp-PLM:
PALMITIC ACID

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ACD:
ARACHIDONIC ACID

ChemComp-NI:
NICKEL (II) ION

Source
  • talaromyces marneffei pm1 (fungus)
KeywordsLIPID BINDING PROTEIN / palmitic acid / MP1 / LBD1 / arachidonic acid / T.marenffei Mp1p

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