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Structure paper

TitleEngineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateJan 16, 2019 (structure data deposition date)
AuthorsBhat, V.D. / McCann, K.L. / Wang, Y. / Fonseca, D.R. / Shukla, T. / Alexander, J.C. / Qiu, C. / Wickens, M. / Lo, T.W. / Tanaka Hall, T.M. / Campbell, Z.T.
External linksElife / PubMed:30652968
MethodsX-ray diffraction
Resolution2.249 - 2.849 Å
Structure data

PDB-6noc:
Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y) in complex with 8-nt RNA
Method: X-RAY DIFFRACTION / Resolution: 2.849 Å

PDB-6nod:
Crystal structure of C. elegans PUF-8 in complex with RNA
Method: X-RAY DIFFRACTION / Resolution: 2.547 Å

PDB-6nof:
Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y, Q367S) in complex with 8-nt RNA
Method: X-RAY DIFFRACTION / Resolution: 2.251 Å

PDB-6noh:
Crystal structure of FBF-2 repeat 5 mutant (C363S, R364Y, Q367S) in complex with 8-nt RNA
Method: X-RAY DIFFRACTION / Resolution: 2.249 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • caenorhabditis elegans (invertebrata)
Keywordsrna binding protein/rna / PUM repeat protein / RNA binding protein / rna binding protein-rna complex

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