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-Structure paper
Title | Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 63, Year 2019 |
Publish date | Jul 10, 2017 (structure data deposition date) |
Authors | Tomich, A.D. / Klontz, E.H. / Deredge, D. / Barnard, J.P. / McElheny, C.L. / Eshbach, M.L. / Weisz, O.A. / Wintrode, P. / Doi, Y. / Sundberg, E.J. / Sluis-Cremer, N. |
External links | Antimicrob. Agents Chemother. / PubMed:30642934 |
Methods | X-ray diffraction |
Resolution | 1.85 - 3.502 Å |
Structure data | PDB-5wep: PDB-5wew: PDB-6c3u: |
Chemicals | ChemComp-A81: ChemComp-ZN: ChemComp-MN: ChemComp-NY2: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | transferase/transferase inhibitor / fosfomycin / FosA / FosA3 / glutathione S-transferase / ANY1 / TRANSFERASE / transferase-transferase inhibitor complex / FosAKP / TRANSFERASE/INHIBITOR / ANY2 / TRANSFERASE-INHIBITOR complex |