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-Structure paper
Title | De novo design of potent and selective mimics of IL-2 and IL-15. |
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Journal, issue, pages | Nature, Vol. 565, Page 186-191, Year 2019 |
Publish date | May 16, 2018 (structure data deposition date) |
![]() | Silva, D.A. / Yu, S. / Ulge, U.Y. / Spangler, J.B. / Jude, K.M. / Labao-Almeida, C. / Ali, L.R. / Quijano-Rubio, A. / Ruterbusch, M. / Leung, I. ...Silva, D.A. / Yu, S. / Ulge, U.Y. / Spangler, J.B. / Jude, K.M. / Labao-Almeida, C. / Ali, L.R. / Quijano-Rubio, A. / Ruterbusch, M. / Leung, I. / Biary, T. / Crowley, S.J. / Marcos, E. / Walkey, C.D. / Weitzner, B.D. / Pardo-Avila, F. / Castellanos, J. / Carter, L. / Stewart, L. / Riddell, S.R. / Pepper, M. / Bernardes, G.J.L. / Dougan, M. / Garcia, K.C. / Baker, D. |
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Methods | X-ray diffraction |
Resolution | 1.999 - 2.516 Å |
Structure data | ![]() PDB-6dg5: ![]() PDB-6dg6: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-HOH: |
Source |
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![]() | BIOSYNTHETIC PROTEIN/Protein Binding / cytokine mimetic / cytokine receptor complex / BIOSYNTHETIC PROTEIN / BIOSYNTHETIC PROTEIN-Protein Binding complex |