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Structure paper

TitleDouble Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Journal, issue, pagesCell Rep, Vol. 26, Page 438-446.e5, Year 2019
Publish dateDec 4, 2018 (structure data deposition date)
AuthorsLu, X. / Xiao, H. / Li, S. / Pang, X. / Song, J. / Liu, S. / Cheng, H. / Li, Y. / Wang, X. / Huang, C. ...Lu, X. / Xiao, H. / Li, S. / Pang, X. / Song, J. / Liu, S. / Cheng, H. / Li, Y. / Wang, X. / Huang, C. / Guo, T. / Ter Meulen, J. / Daffis, S. / Yan, J. / Dai, L. / Rao, Z. / Klenk, H.D. / Qi, J. / Shi, Y. / Gao, G.F.
External linksCell Rep / PubMed:30625326
MethodsX-ray diffraction
Resolution2.4 - 3.6 Å
Structure data

PDB-6ivz:
Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-6iw0:
Crystal structure of 5A ScFv in complex with YFV-17D sE in postfusion state
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

PDB-6iw1:
Crystal structure of YFV-17D sE in postfusion state
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-6iw2:
Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-6iw4:
Crystal structure of YFV-17D sE in prefusion state
Method: X-RAY DIFFRACTION / Resolution: 2.801 Å

PDB-6iw5:
Crystal structure of YFV-China sE in prefusion state
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • yellow fever virus
  • homo sapiens (human)
  • yellow fever virus (strain 17d vaccine)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Yellow fever virus / Neutralizing monoclonal antibody / Envelope protein / Flavivirus / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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